August 20, 2024 – The “Company” today announced that the Company’s proprietary molecule, IGC-1A, has been identified as a potential GLP-1 agonist, as a result of the Company’s state-of-the-art Artificial Intelligence (“AI”) modeling. This discovery highlights the versatility of IGC Pharma’s drug platforms and marks the Company’s potential for strategic expansion to metabolic disorders and weight loss.

Identifying IGC-1A as a potential GLP-1 agonist marks a significant milestone for IGC Pharma, presenting a substantial market opportunity and improving patient care for various conditions. GLP-1 (glucagon-like peptide-1) is a powerful hormone known for its dual role in managing blood sugar levels and promoting weight loss. As GLP-1 agonists gain traction for their effectiveness in treating type 2 diabetes and aiding weight management by increasing satiety and reducing appetite, they are also being explored for their neuroprotective benefits. This could potentially revolutionize treatments for Alzheimer’s disease by addressing inflammation and oxidative stress, offering a multifaceted approach to improving patient outcomes.
Ram Mukunda said: Our AI-driven approach has revealed a promising opportunity for IGC-1A and IGC-1C to be potential GLP-1 agonists. This discovery strengthens our Alzheimer’s treatment portfolio and also positions us to potentially enter the rapidly growing weight loss market. By comparing IGC-1A and IGC-1C with established drugs such as Ozempic, Tirzepatide, Retatrutide, and Metformin, among others, our AI model indicates that they could become an effective option for metabolic disorders. While we are in the early stages, our molecules allow us to potentially build a portfolio that also focuses on metabolic disorders and obesity with improved tolerability and efficacy compared to current options.
As we advance toward further validation through clinical trials, we see substantial growth potential in developing innovative treatments that address metabolic and neurodegenerative conditions. Additionally, investigations into IGC-1A have revealed its potential as a GLP-1 agonist, GIP agonist, and a CB1r inverse agonist, opening new avenues for potentially impactful therapies in weight management, neurological disorders, and metabolic disorders.”
In 2024, IGC Pharma anticipates progressing toxicology and dosing studies in preparation for submitting an Investigational New Drug Application for IGC-1A to the FDA although there can be no assurance thereof. IGC Pharma’s potential strategic expansion to metabolic disorders underscores the Company’s commitment to leveraging advanced AI technology to drive innovation and develop impactful solutions that create substantial value for investors.
“We believe our early prediction AI initiatives can offer significant hope to patients and caregivers, create long time value for shareholders, and alleviate the projected $1 trillion economic burden on the U.S. healthcare system from Alzheimer’s disease”.
About IGC Pharma S.A.S.
IGC Pharma SAS is at the forefront of integrating artificial intelligence (AI) into drug discovery, clinical research, and early disease detection. We are committed to revolutionizing the pharmaceutical landscape by leveraging AI-driven solutions to enhance Alzheimer’s disease (AD) research, biomarker identification, and patient diagnostics.
Our team of biomedical engineers, data scientists, and clinical researchers utilizes advanced AI models to accelerate drug development, optimize clinical trials, and improve early detection of neurodegenerative diseases. We apply cutting-edge deep learning techniques to analyze vast datasets, uncover novel therapeutic targets, and refine treatment strategies.
With a strong foundation in AI-powered analytics, IGC Pharma SAS is dedicated to pioneering the next generation of precision medicine, ensuring that breakthroughs in neuroscience and drug discovery translate into effective, accessible treatments for patients worldwide.
Join us in reshaping the future of healthcare through the power of AI.